Transgelin expressing myofibroblasts orchestrate ventral midline closure through TGF-β signalling
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چکیده
منابع مشابه
Transgelin-expressing myofibroblasts orchestrate ventral midline closure through TGFβ signalling
Ventral body wall (VBW) defects are among the most common congenital malformations, yet their embryonic origin and underlying molecular mechanisms remain poorly characterised. Transforming growth factor beta (TGFβ) signalling is essential for VBW closure, but the responding cells are not known. Here, we identify in mouse a population of migratory myofibroblasts at the leading edge of the closin...
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ژورنال
عنوان ژورنال: Development
سال: 2017
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.152843